Isabel Cleves Dodge Sloane (February 1896 – March 16, 1962) was an American heiress and socialite who owned a major Thoroughbred horse racing stable and breeding farm.

Educated at Detroit's exclusive Liggett School for Girls, her family's great wealth brought her in contact with America's social elite and in 1921 she married Manhattan stockbroker, George Sloane.

Keeping her married name, Isabel Dodge Sloane owned homes in Locust Valley on Long Island and on Park Avenue, but in 1929 she purchased an 850-acre (3.4 km2) property in Upperville, Virginia that she called Brookmeade Farm and entered the horse breeding part of the business.

In a 1939 article in the New York World-Telegram, feature writer Elliott Arnold wrote that there wasn't a man in the business who knew more about Thoroughbreds than Isabel Dodge Sloane.

In 1934 she became the first woman to lead the American owners' list when she won the Kentucky Derby with future Hall of Fame colt Cavalcade and the Preakness Stakes with High Quest.