Isabel de los Ángeles Ruano (born June 3, 1945, in Chiquimula) is a Guatemalan writer, poet, journalist and teacher.
She graduated from Educación Primaria Urbana with a teacher's diploma in 1964 at the age 18.
In 1978, she completed her university studies in Spanish and Latin American Language and Literature at the Universidad de San Carlos de Guatemala.
She was awarded the Miguel Ángel Asturias National Prize in Literature by the Ministry of Culture in 2001.
Dressing as a man, she has lived for several years in Guatemala City's colonia Justo Rufino Barrios, zona 21.