[12] Fontana appeared in the Valentino advertisting F/W 1999 advertising campaign photohraphed by Mario Testino along with Gisele Bündchen, Audrey Marnay, and Aurelie Claudel.

[1] Since 1999 she has modeled for Sports Illustrated Swimsuit Issue, Marie Claire, ELLE, Vogue, Harper's Bazaar, Numéro, i-D, Arena and many others.

Fontana rose to prominence after appearing on the cover of Vogue US in 2004 along with Natalia Vodianova, Daria Werbowy, Gemma Ward, Liya Kebede, Gisele Bündchen, Karen Elson, Karolina Kurkova and was photographed by Steven Meisel.

She also appeared on numerous advertising campaigns that same years such as Versace F/W 08, Balenciaga S/S 08, Pepe Jeans, Roberto Cavalli, H&M, Flowerbomb, Valentino.

[4] In 2008, Fontana made her debut on the Forbes The World's 15 Top-Earning Models list at place 11, having earned $3 million.

[14] In 2009, she was featured as a 'Face of the Moment' in May 2009's US Vogue and appeared on the Viktor&Rolf and Revlon Fair, Fragrance campaigns.

[6] Fontana has been the face of a variety of advertising campaigns including Shiatzy Chen, Armani Jeans, Chanel, Bulgari, Colcci, Disritmia, Dolce and Gabbana, Emporio Armani, Enrique Martinez, Escada, H&M, Helena Rubinstein, Hugo Boss, Hussein Chalayan, Leonisa, Massimo Dutti, Mango M. Officer, Nicole Farhi, Oscar de la Renta, Peter Hahn, Philips, Ralph Lauren, Revlon, Roberto Cavalli, Rosa Chá, Saks Fifth Avenue, Tommy Hilfiger, Triton, Valentino, Versace, Victoria's Secret, Vivara and others.

[1] Photographed by Steven Meisel, she was presented on the September 2004 cover of American Vogue as one of the "Models of the Moment".

[5] Fontana married actor and model Henri Castelli on 10 December 2005, and their son, Lucas, was born on 23 October 2006 in São Paulo.