Isabelle Bowen Henderson House and Gardens is a historic home and garden and national historic district located at Raleigh, North Carolina.

The main house is a modest 19th century turreted late Victorian period frame cottage, with a Colonial Revival style studio wing and kitchen and dining porch added in 1937.

It was the home of noted local artist Isabelle Bowen Henderson and representative of the Williamsburg Revival design movement in Raleigh.

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