At a press conference held at Gleneagles JPMC (GJPMC) on 29 November 2014, Health Minister Adanan Yusof revealed that Brunei's first left ventricular assist device (LVAD) has just been installed in a patient with heart condition.

Mumtazali Mohd Abdul Aziz, 51, reportedly had a mechanical heart implant that allowed him to lead a somewhat normal life following surgery.

[10] At a press conference held at the MOH on 13 April 2020, Dato Isham said that the development of patients testing positive once more for COVID-19 is extremely concerning because it is still unknown how the new virus infects and how it will evolve.

Dato Isham stated:[13]MOH Intelligence Hub in EVYD Campus demonstrates the strategic relationship among healthcare technology, data analytics, research and policy planning.

In addition, he emphasized the necessity for continuous monitoring based on transparency and the use of digital technology to link information throughout the world, as well as for assessing, modernising, and reforming the global health security system.

Despite the government's best efforts, the minister noted, chronic health problems including diabetes, malignancies, and heart disease remain on the rise.

[16][17] At the 7th Annual Scientific Meeting of the Cardiac Society of Brunei Darussalam, Dato Isham stated that overall, cardiovascular disease-related premature mortality rose from 20% in 2013 to 26% in 2018.

[18] Isham Jaafar paid a visit to the School of Public Health NUS on 8 February 2023 as part of follow-up conversations following the signing of an Memorandum of Understanding (MoU).

He was joined by members of the Brunei High Commission as well as his wife, Datin Dr. Hajah Norsurainah @ Noraslinah binti Haji Ramlee.