[2] Blavatsky gathered a number of themes central to the occult tradition—perennial philosophy, a Neo-Platonic emanationist cosmology, adepts, esoteric Christianity—and reinterpreted them in relation to current developments in science and new knowledge of non-Western faiths.

In doing so, Isis Unveiled reflected many contemporary controversies—such as Darwin's theories on evolution and their impact on religion—and engaged in a discussion that appealed to intelligent individuals interested in religion but alienated from conventional Western forms.

[13] Similarly, historian Geoffrey Ashe noted that Isis Unveiled combines "comparative religion, occultism, pseudoscience, and fantasy in a mélange that shows genuine if superficial research but is not free from unacknowledged borrowing and downright plagiarism.

[16] Likewise, Henry R. Evans, a contemporaneous journalist and magician, described the book as a "hodge-podge of absurdities, pseudo-science, mythology and folk-lore, arranged in helter-skelter fashion, with an utter disregard of logical sequence.

[4][12] Sten Bodvar Liljegren notes that in addition to contemporaneous occult sources and the prevailing orientalism of the period, the novels of Edward Bulwer-Lytton heavily influenced Blavatsky's Theosophical ideas.