A pre-Isluga unit containing Cabay volcano, northeastern Carcanchuni and southern Cerro Blanco are not stratigraphically controlled.

[2] Further, Isluga and Tata Sabaya and some other volcanoes form a lineament which may coincide with the suture between the Chilenia terrane and the Arequipa-Antofalla block.

The volcano hosts some of the Andes' largest thermal anomalies in satellite images and increased fumarolic activity in 2002–2003 was reported.

[8] The climate of the region varies by altitude; between 2,800–4,000 metres (9,200–13,100 ft) lies a borderline desert area with temperatures ranging from below 0 °C (32 °F) to 10 °C (50 °F), with most precipitation (50–200 millimetres per year (2.0–7.9 in/year)) falling in summer.

[4]: 5  A similar climate lies on the eastern part of the mountains between 3,000–4,000 metres (9,800–13,100 ft), with 100–200 millimetres per year (3.9–7.9 in/year) precipitation.

[4]: 5 Also named Laram Qhawani, the volcano dominating the village of Enquelca is a sacred mountain, responsible for health, wealth and rain.

While no archeological remains have been found on its summit, a triangular stone structure resembles the patterns drawn when making offerings to spirits.

[16] Threats from future eruptions of Isluga consist primarily in the contamination of aquifers and destruction of agricultural areas by ash falls, both limiting factors in the desertic environment surrounding the volcano.

Evolución geológica y magmática del volcán Isluga, 19° S, región de Tarapacá, Chile (Thesis) (in Spanish).