Borrero was known for his energetic approach to fostering social and charitable initiatives and towards the end of his tenure sought to establish new parishes and reorganize their structure.

Borrero received his ordination to the priesthood on 19 December 1896 from Lucido Maria Parocchi in the Basilica of Saint John Lateran before remaining in Rome to continue with further studies.

[1][2] Borrero returned to Neiva in his homeland in 1899 before becoming the vice-rector for Garzón in the Huila Department thus seeing him monitor the education of seminarians; he was later made chancellor for the Tolima diocese.

[2] He served from 1908 until 1919 as the secretary for the Colombian Episcopal Conference while Pope Pius XI named him on 5 February 1923 to be both the coadjutor for the Bogotá archdiocese in addition to Titular Archbishop of Traianopolis in Rhodope.

The national government was not too pleased with Borrero becoming the archbishop and more so after his involvement in the 1930 presidential election that saw his favored conservative candidate Alfredo Vásquez Cobo lose.

[1][2] The informative process for the beatification cause launched in the late prelate's archdiocese on 31 January 1962 and concluded just a few months later on 12 September; the cause remained inactive until it was reopened on 1 June 1979 thus allowing for a second local investigation to be opened on 10 May 1982.