Isoa Ulago Domolailai (born Sigatoka, 13 January 1981) is a Fijian rugby union footballer.
Domolailai's first game for Fiji was on 10 November 2001, in a 10–66 loss to Italy.
He missed the 2003 Rugby World Cup finals, due to an injury, but was selected again for the 2007 Rugby World Cup finals.
He played, as a substitute, in the 12–55 loss to Australia, on 23 September 2007.
Domolailai currently holds 13 caps for the Fijian Squad, having yet to score his first points.