[1] She was a powerful political figure in Scotland during the youth of King James V, and her wealth and influence attracted misogynous comment from her faction's enemies.
[4] In January 1505, Richard handed a newly built house on the north side of the Royal Mile to his other son, Master Henry Hoppar.
[8] Isobel's nephew, Katrine's brother, Adam Hopper (d. 1529), was master of the Edinburgh Merchants Guild, established by "seal of cause" in 1518 when it was given the Holy Blood Aisle in St Giles Kirk.
[10] Isobel Hoppar married, before January 1504, Master John Murray of Barony or Blackbarony near Peebles, a clerk of the exchequer, who was killed at Flodden in 1513.
[12][13] After John Murray's death at Flodden, Isobel Hoppar was described as a "rich widow of Edinburgh" in 1515 by Baron Dacre.
[18] Her contemporary, the Jedburgh monk Adam Abell reflected on the career of Kilspindies' wife at this time in his chronicle The Roit and Quheil of Tyme.
He was surprised by her involvement in public affairs, and he claimed that her influence and manners had had a negative effect on the Earl of Angus;"His pridefull wife Dik Oppar's douchter of Edinburgh wes callit my lady thesaurer, and it is saide sche wes ane compositor in the justice airis.
If his family was forced into exile, Lassels would provide a chamber at Norham for Margaret Douglas, and Isobel Hoppar would wait on her.
The English diplomat Thomas Magnus noted that Isobel was a powerful character in the Douglas family dynamic.
In February 1529 Isobel's lands at Staneburn near Linlithgow were given to Gavin Hamilton, and her rents, crops, and livestock at Blackbarony and 'Puro' (which she held conjointly with her husband) were given to Patrick Hepburn of Wauchtoun.