"Isolation" is a song by American rock band Alter Bridge, released as the first single from its third album, AB III.

The lyrics explore metaphorically isolating oneself from faith and belief, a common theme throughout the record.

Several active rock radio stations in the United States put the song in regular rotation several weeks before its U.S. release.

Originally described by singer Myles Kennedy as a "real heavy track,"[1] the song was debuted after much anticipation by Roadrunner Records on their website on September 6, 2010 with the announcement that it would be released as the first single from AB III.

Unlike most Alter Bridge singles, it is very heavy and aggressive, both musically and lyrically, and showcases the band's style, along with elements of speed metal and a strong melody, which has been noted by critics.

"[5] Myles Kennedy said about the song: "I remember Mark [Tremonti] playing me the riff and the overall music, and he had some great melodies for it as well.

[8] "Isolation" received positive feedback from several professional reviewers, including Rob Laing from MusicRadar, who praised it for its speed metal influence.

[8] Rick Florino from Artistdirect said that the song "rolls from a thrash breakdown into one of the catchiest refrains that the band has committed to tape.