Branches erect, parallel to each other, all almost the same length, curved at the base, with the apex attenuated, up to 10 meters long and 5–15 cm in diameter.

The scentless tubular flowers grow near the shoot tips and bloom multiple times, sometimes forming small crowns.

The edible fruits are subglobose to ellipsoid, remain green for some time, then turn orange to red, and measure 2.5–3.5 cm in length.

They are covered in small red scales and contain black seeds approximately 1.5 mm in size.Fruits have red pulp, 3 to 4 cm long and 2 to 3.5 cm wide, covered with short podaries arranged in 4 series, with areoles provided with a reduced deltoid basal scab and short emerging felt, with very short spines, dehiscent at its apical part, giving off a pleasant aroma similar to that of jasmine, very juicy, fleshy and sweet when ripe[3] [4] Isolatocereus dumortieri is native to several Mexican states, including Aguascalientes, Guanajuato, Guerrero, Hidalgo, Jalisco, México, Michoacán, Morelos, Oaxaca, Puebla, Querétaro, San Luis Potosí, Veracruz, and Zacatecas at elevations between 1100 and 2200 meters.

[6] First described as Cereus dumortieri by Michael Joseph François Scheidweiler in 1837, the genus name "Isolatocereus" derives from the Italian word isolato (isolated).