Ispica (Sicilian: Spaccafurnu, Latin: Hyspicae Fundus) is a city and comune in the south of Sicily, Italy.

The first mention in a document of Ispica occurred in 1093, in a list of churches and ecclesiastic departments for administrative purposes, but the territory has been colonized since the Bronze Age.

The main economical activity consists of farming and organic products, especially carrot, zucchini, tomatoes, olives, vineyards.

The town also hosts examples of Sicilian Baroque architecture such as the Vincenzo Sinatra's Basilica di Santa Maria Maggiore, the Annunziata Church, the Carmine monastery, and the St. Barthelemy cathedral.

This cave, the most important in Eastern Sicily, is 13 kilometres (8 mi) long and is divided among two other comunes, Modica and Rosolini.