Liberia would receive two state visits from Israel, one from President Yitzhak Ben-Zvi to Monrovia in August 1962, and one from Prime Minister Levy Eshkol in June 1966.

During the OAU summit in Rabat in June 1972, Liberia supported a resolution calling for Israel to withdraw from occupied territories acquired in the Six-Day War.

[6] On 2 November 1973, the Tolbert administration severed ties with Israel in response to the Yom Kippur War, along with 28 other African countries.

[7] While their formal relations were undone, Liberia maintained some contact with Israel through intermediates, such as private Israeli businesses and international organizations like the United Nations.

[2][8] On 12 April 1980, Tolbert was killed in a coup d'état led by Samuel Doe, who became Liberian head of state.

[2] Initially, leading officials in Doe's regime wanted to preserve a foreign policy more aligned with the Soviet Union and Arab nations.

[10] In a time when the Doe regime's authoritarian practices made it the target of economic sanctions from the United States Congress, the Reagan administration used Israel as an indirect way to preserve ties between the U.S. and Liberia.

[12] On 8 June 2022, Liberia announced its intention to open a trade mission in Jerusalem which is intended, over time, to become an embassy.

[14] On 12 December 2023, Liberia voted with Israel and eight other countries in the United Nations General Assembly, opposing a resolution calling for an immediate cease-fire in Gaza amidst the Israel–Hamas war.

[16] As of September 2023, the current ambassador from Israel to Liberia is Roey Gilad, who is also accredited to Ghana and Sierra Leone.