ICA co-owner Sylvan Adams was the driving force behind the Giro's "Big Start" in Israel, having financed a significant part of the race budget.

ICA's best performance in the Giro was recorded in the 18th stage, when its Spanish rider Ruben Plaza finished in second place.

Three days later when the team completed the Giro in Rome, Guy Sagiv became the first-ever Israeli cyclist to finish a grand tour.

[5] In July 2020, it was announced that seven-time Grand Tour winner Chris Froome would join the team for the 2021 season.

[11][12] In the 2021 Giro d'Italia in May, Italian rider Alessandro De Marchi briefly wore the maglia rosa as leader of the general classification after Stages 4 and 5, while Dan Martin won Stage 17 and finished tenth overall, and Davide Cimolai finished second in the Points classification.

[14] The season was largely disappointing for IPT, as they struggled for results and faced the threat of relegation from the UCI World Tour.

The team was relegated from the World Tour at the end of the 2022 season after finishing 20th in the points standings for the 2020 - 2022 qualification cycle.

[17] IPT was awarded a wildcard entry to the 2023 Giro d'Italia after both Lotto-Dstny and Team TotalEnergies declined to take part[18] and was also invited to the 2023 Tour de France,[19] meaning that with the exception of the Vuelta a España their 2023 race programme will be largely unaffected by their relegation.