"It's Okay (One Blood)" is a song by American rapper and West Coast hip hop artist The Game featuring vocals from reggae singer Junior Reid, from his second studio album Doctor's Advocate.

Released as the album's lead single on July 24, 2006, the song was written by The Game himself and Junior Reid, and it was produced by D-Roc, and Reefa.

Several lines in the song stirred controversy as to who the lines were aimed at: "You 38 and you still rapping, ugh", was aimed at Jay-Z, as well as a diss at snap music; "Turn on the TV and all you see is the A/You niggaz better make up a dance and try to get radio play/Keep on snapping your fingers, I ain't going away."

After people thought he made a diss to Atlanta, GA, The Game later clarified who he was referring to in a radio interview with HOT 107.9 and said the following: Banks and Buck have albums coming out near to mines, you know what I'm saying?

[2] In the song, The Game mentions the following rappers, in order, and some repeated: Dr. Dre, 50 Cent, Snoop Dogg, Eazy-E, Young Jeezy, Lil Jon, The Notorious BIG, Ice Cube, Nas and 2Pac.

This song is also included in the video game Def Jam: Icon for the PlayStation 3 Xbox 360.

[4] The video features revised lyrics in order to accommodate television decency standards.