It's a Mad, Mad, Mad, Mad Marge

After a failed marriage attempt with Otto, Becky (played by guest actress Parker Posey) stays with the Simpson family.

Homer then passes out face first in a large Noah's Ark-themed bowl of ice cream, prompting Becky to give him mouth-to-mouth, which Marge sees and thinks she is kissing him.

She attacks Becky but is arrested and sent to a sanity hearing, where due to her past affection for Ringo Starr and her belief in God, the certifying board decide to commit her.

The writers of The Simpsons were told that actress Drew Barrymore wanted to guest star in the series and pitched several possible episodes for her.

[3][4] Scully gave the guest role to him as a thanks for his practical joke he played on fellow writer Matt Selman regarding East St. Louis and the season ten episode "They Saved Lisa's Brain".

[1] The producers got a censor note for the scene where Chief Wiggum teaches Ralph how to hold a gun in order to achieve a "kill shot".

[5] The jimmies that Marge throws at the busboys are all variations of the character design that was used for the Squeaky Voiced Teen since the series' inception.

Selman, in the episode's audio commentary, recalled that it was hard to write so many misunderstandings; Scully commented, "It gives us a new appreciation for Three's Company.

When Otto plays air guitar, it is completely accurate fingering: John Achenbach, a storyboard artist on the show, is an accomplished guitarist and provided demonstrations for the animators.

The music that accompanies Homer’s use of a sly gadget to extract pastry segments from within Otto's wedding cake is an homage to the James Bond Theme.

Staff members Mike Scully, George Meyer, Ian Maxtone-Graham, Matt Selman, Larry Doyle, and Steven Dean Moore participated in the DVD audio commentary for the episode.

[10] While reviewing the eleventh season of The Simpsons, DVD Movie Guide's Colin Jacobson commented: "Unusually, 'Mad' provides a pretty concise focus on only one story.