Its deterioration in time has brought the need for restoration to many of its facilities, including the side and rear facades, which was done with funding supplied jointly by the Uruguayan and Italian governments in 2003.

Not until the mid-nineteenth century, did Uruguay manage to put an end to a series of irregularities that were not helpful in solving the internal party crisis.

The initial objective of the institution created under the supervision and direction of the italo-Uruguayan architect Luis Andreoni, was to provide basic health services, to confront the high percentage of infant mortality, product of the scarcity of resources and of public access to hospitals.

From the work and management of Garibaldi, several tributes emerged to his figure, among which one avenue in Montevideo which bears his name, a monument in his memory in the city of Salto and an Italian hospital in Buenos Aires.

This is known commonly as the "migración transformadora", because during this period, Uruguay experienced significant changes in style and quality of life of its population.

In an effort to revive a classic model, materials such as marble, granite and azulejo are used, imported from Europe, to recreate an image that combines the nuances of ancient art with the advances of modern science.

Finally, the wing on the side of Artigas Boulevard, known as the "Passiva of the Hospital Italiano", is a bracket of bronze sculptures and figures that commemorate great personalities of both Italy and Uruguay.

Despite the physical deterioration of the facility and the sequestration (because of debts) that happened in early 2004, joint efforts by representatives of the government Italian in Uruguay, and of the Uruguayan Medical Union (Sindicato Médico Uruguayo) (SMU) have been able to counter the debt and the deterioration of the hospital, bringing donations for the renovation and improvement of its interior and exterior.