It deals with production, economic activities, energy and mineral resources, telecommunications, consumers, tourism, internationalisation and business incentives.

[7] With the fall of Fascism, the Badoglio I Cabinet abolished the last one and recreated the Ministry for Industry, Trade and Labour.

[14] Only in 2008 the Bassanini reform was re-established and the MiSE included the functions of the Ministries of Communication and International Trade, which ceased to exists with the Berlusconi IV Cabinet.

The Minister is a member of the High Council of Defence[20] and appoints the General Secretary of the Italian Competition Authority.

[21] As of 15 July 2019, MiSE oversees the following public entities:[22] As of 4 and 11 July 2019, MiSE holds the following shares:[24] As of 4 July 2019, MiSE owns the following entities:[25] The Ministry is formed by the Cabinet offices collaborating directly with the Minister, the General Secretary Office, 14 General Directions (Direzioni generali, DG) and various commissions and committees.