[4] Alvise Da Mosto, built at the Cantieri Riuniti del Quarnaro in Fiume, was laid down on 22 August 1928, launched on 1 July 1929 and completed on 15 March 1931.

Between 1936 and 1937 she participated in Italian naval operations linked to the Spanish Civil War, escorting ships that carried troops and supplies for Francisco Franco's forces from Italy to Spain.

[6] When Italy entered World War II, on 10 June 1940, Da Mosto was undergoing modification work to her bow in the La Spezia Naval Arsenal, and she only re-entered service in August 1940, and was assigned to the 15th Destroyer Division.

[6] On 30 November 1941, Da Mosto sailed from Trapani to escort to Tripoli the tanker Iridio Mantovani, carrying, 8,600 tons of fuel for the Axis forces in North Africa.

Da Mosto engaged the British ships in a last attempt to save as many survivors as possible from the sinking tanker, but was hit multiple times, including in one of her magazines, and quickly sank at 18:15 in 33°53' N, 12°28' E, about 75 miles northwest of Tripoli.

Mantovani's blazing wreck was also finished off by Force K. 138 members of Da Mosto's crew were killed, while 125 survivors were later rescued by the Italian torpedo boat Generale Marcello Prestinari.