Scirè (S 527) is a Todaro-class submarine of the Italian Navy.

The submarine was laid down on 27 July 2000 at the Muggiano shipyard by Fincantieri.

She participated in some of the operations of the Decima Flottiglia MAS, including the raid on Alexandria in 1941 using human torpedoes, before her loss in 1942.

Scirè spent over five months deployed to the U.S. in 2009, participating in the CONUS 2009 exercise with the United States Navy.

This article about a specific military ship or boat of Italy is a stub.