[1] The second ship was the Amerigo Vespucci, built in 1930 at the (formerly Royal) Naval Shipyard of Castellammare di Stabia (Naples).

Bow and stern are decorated with intricate ornaments; she has a life-size figurehead of Amerigo Vespucci.

Most of her training cruises are in European waters, but she has also sailed to North and South America, and navigated the Pacific.

[6] While sailing the Mediterranean Sea in 1962, the American aircraft carrier USS Independence flashed the Amerigo Vespucci with the light signal asking: "Who are you?"

"[7] In 2022, the Amerigo Vespucci sailed by the American aircraft carrier USS George H.W.

Starting from 2013, the Vespucci depends directly on the Commander in Chief Naval Fleet.

On 22 November 2024, Amerigo Vespucci conducted a joint sailing exercise with the INS Taringi of the Indian Navy off the coast of Kochi, India.

[10] As of 30 November 2024, the ship is docked at Mumbai for a five-day stopover as a part of its circumnavigation that started in 2023 and includes 36 ports and 32 countries.

[11] On 9 January 2025, archbishop Santo Marcianò of the Military Ordinariate of Italy designated ship as a 2025 Jubilee church and site “for sacred pilgrimages and for pious visits among its missions at sea.”[12] In April 2015 tender NC90 was replaced by the following:[13]