Italy forfeited its round of 16 match with Spain, then was defeated by Greece in the bronze medal tournament.
Frigerio gave the nation its first gold medals in the sport by winning both of the racewalking competitions.
Garzena had the best performance for Italy, taking all three of the nation's wins on his way to a bronze medal.
Italy took its first Olympic cycling medal when its pursuit team won the gold.
Italy also had three cyclists place in the top eight of the 50 kilometres event, though none was able to secure a medal.
Nedo Nadi took the individual gold medals in the foil and sabre; both he and his brother Aldo were on all three of the gold-medal teams.
In the tournament for second place, the Italians beat Norway before losing to Spain in the consolation semis.
Italian rowers reached the finals for the first time, winning the nation's first two Olympic rowing medals: a gold in the coxed pairs and a silver in the double sculls.
Italy's best result was a fourth-place finish in the team standing military rifle.
Balbi and Colombo reached the quarterfinals in the men's doubles, the best result for Italy that year.
Because the Dutch went on to win the silver medal, Italy received an opportunity to contest the bronze.
In the bronze medal semifinals, the Italians lost again, this time to the United States, to finish fifth and last in the tournament.
No Italian weightlifter placed worse than sixth, with two winning medals (including Bottino's gold) and two others just missing with fourth-place finishes.
None of the Italian wrestlers advanced past the quarterfinals, or qualified for the silver or bronze rounds.