[1] Since then, it has won the contest on three occasions: in 1964 with the song "Non ho l'età" performed by Gigliola Cinquetti, in 1990 with "Insieme: 1992" by Toto Cutugno, and in 2021 with "Zitti e buoni" by Måneskin.

Italian broadcaster RAI confirmed that the performer that would represent Italy at the Eurovision Song Contest 2022 would be selected from the competing artists at the Sanremo Music Festival 2022, the 72nd edition of the event.

According to the rules of Sanremo 2022, the winner of the festival earns the right to represent Italy at the Eurovision Song Contest, but in case the artist is not available or refuses the offer, the organisers of the event reserve the right to choose another participant via their own criteria.

For the third year in a row, Amadeus served as the artistic director and presenter of Sanremo,[2] and was joined on stage by Ornella Muti, Lorena Cesarini, Drusilla Foer, Maria Chiara Giannetta and Sabrina Ferilli, each on a different night.

Six former Eurovision Song Contest entrants were among the competing artists: Iva Zanicchi (1969), Gianni Morandi (1970), Massimo Ranieri (1971 and 1973), Emma (2014), Fabrizio Moro (2018) and Mahmood (2019).