Itamarandiba (Portuguese pronunciation: [itamaɾɐ̃ˈdʒibɐ]) is a Brazilian municipality located in the north-center of the state of Minas Gerais.

[3] Itamarandiba is located at an elevation of 910 meters near the headwaters of the Rio Araçuai, which flows north into the Jequitinhonha River.

Neighboring municipalities are: Diamantina, Aricanduva, Carbonita, Turmalina, Capelinha, Senador Modestino Gonçalves, Veredinha, Rio Vermelho, São Sebastião do Maranhão, Água Boa, and Coluna.

The planting of eucalyptus for charcoal production is important and coffee cultivation has been increasing in recent years.

The highest ranking municipality in Minas Gerais in 2000 was Poços de Caldas with 0.841, while the lowest was Setubinha with 0.568.