The team was first presented to the public in Bedizzole, Italy, in 2010, with the team's first race being the Gran Premio dell'Insubria-Lugano in Switzerland.

Russian rider Alexander Mironov won Itera–'s first ever UCI race in the one-day race, Trofeo Franco Balestra, in Brescia, Italy.

During the 2011 season the team scored 29 victories, 22 second and 20 third places.

In 2012 Anton Vorobyev became the Under-23 World Time Trial Champion after winning the individual time trial of the UCI Road World Championships in the Netherlands, he secured the first Russian gold medal in the Under-23 category since 2005.

In November 2015, Andrey Lukonin and Ivan Lutsenko were banned for a year for breaching anti-doping regulations.