[2] Khune shot to fame when he saved three penalties from Esrom Nyandoro and Peter Ndlovu against Mamelodi Sundowns in the Telkom Knockout final on 1 December 2007.

[4] He is also famous for performing a René Higuita scorpion kick save in a league victory over Mpumalanga Black Aces on 28 October 2015,[5] which made rounds in England.

[8] Unlike many South African players who cite kicking a football on their hometown's dusty streets as their starting point, Khune was in love with cricket idolising Nicky Boje.

His younger brother Lucky Khune previously played as a striker for Chiefs and currently for PSL side Chippa United.

[9] Khune started out as a striker when he arrived for trials at Chiefs in 1999, but assumed the gloves by chance after he experienced chest problems during a junior game and found himself being reduced to a ball boy.

After three years of waiting to get any game time, Khune finally got his opportunity in the early stages of the 2007–08 season after the departure of number one goalkeeper Rowen Fernandez to German club Arminia Bielefeld.

His first season in the top-flight was highly successful as several match-winning displays for his side earned him a host of individual awards with Chiefs having the best defensive record in the league conceding only 19 goals in 30 games.

During the 2009–10 season a finger injury sidelined Khune for three months giving understudy Arthur Bartman a chance to play regularly in his absence.

[12] In the 2013–14 season he won the Goalkeeper of the Year award for the second time in a row with 15 goals conceded and 18 clean sheets in 25 starts beating Moeneeb Josephs and Anssi Jakkola.

[15] He was declared fit to play on 23 February 2015 although he did suffer a minor injury after clashing Morgan Gould's studs to his ribs which left a mark in a 4–0 win over Edu Sports in the Nedbank Cup.

[16] On 9 April 2015 in a 1–0 win over AmaZulu, Khune was controversially sent off in the 82nd minute in a game which also produced nine yellow cards – after receiving two cautions in quick succession from referee Phillip Tinyane at Peter Mokaba Stadium.

Khune was selected for the 2010 FIFA World Cup as Carlos Alberto Parreira's first-choice goalkeeper and made some good saves in the opening match against Mexico.

He arrived at the tournament as the player with the most international experience, alongside Nigeria's Mikel John Obi, with 75 national team caps to his name.