Born in Croatia, Krstić received a scholarship to attend the Cranbrook Kingswood school in Michigan, U.S, when he was 15.

[2] In 2004, he enrolled at Harvard College but took a year's leave to work on secure electronic healthcare at Croatia's largest children's hospital.

After returning to Harvard in 2005, he took another leave when offered a position with One Laptop per Child.

While there, he designed the Bitfrost security architecture and personally oversaw the project's first two in-country deployments, in Uruguay[3] and Peru.

In 2007, Krstić became a TR35 laureate, selected by the MIT Technology Review as one of the world's top 35 innovators under the age of 35.