The four districts forming the former territory of the Iwaki clan was given in 1600 as a 100,000 koku domain to Torii Tadamasa, a childhood friend of Ieyasu.

Under early Naitō rule, the domain implemented numerous fiscal reforms, developed large amounts of new rice lands, and constructed massive irrigation works.

However, this prosperity did not last long, as later Naitō rulers were very young and often dissolute, preferring to leave government matters in the hands of subordinates, who often formed rival cliques, leading to O-Ie Sōdō.

A series of crop failures caused by implement weather led to a peasant revolt in 1738, at which point the Tokugawa shogunate stepped in, and transferred the Naitō to Nobeoka Domain in distant Kyushu.

However, after serving as jisha-bugyō and wakadoshiyori and from 1783 as rōjū, his revenues were supplemented with an additional 17,000 koku from his former holdings in Mino.

The Andō clan continued to rule Iwakitaira domain through the remainder of the Edo period.

The final daimyō of Iwakitaira, Andō Nobutake, surrendered to the Meiji government in March 1868, even before the Battle of Iwaki, and had been confirmed in his titles in April.

However, in December he was told that he would not be allowed to return to Iwakitaira, but would be given a new 34,000 koku domain in Iwai District, Rikuchu Province.

Nobutake protested the decision, and after paying a 70,000 ryō fine on August 3, 1869, was permitted to return to Iwakitaira.

Nobunari was the younger son of Andō Nobutada and became daimyō in 1755 at age 12 when his father was sentenced to house arrest over misgovernment of his domain.

Nobunari subsequently served as jisha-bugyō (1781), wakadoshiyori (1784) and rōjū (1793), so that by 1793 he had increased his kokudaka back to 67,000 koku.

He is also noted for establishing a han school in the domain, teaching kanji, the Four Books and Five Classics, Japanese language, calligraphy, military science and rangaku.

In 1858, he rose to the post of jisha-bugyō, and subsequently was appointed a wakadoshiyori under the Tairō Ii Naosuke.

In 1860, Ii Naosuke was assassinated in the Sakuradamon Incident and Nobumasa became a leading councilor of state together with Kuze Hirochika.

[2] He was a supporter of the kobu-gattai policy to strengthen relations between the imperial court and the shogunate and was instrumental in arranging for Kazunomiya, the younger sister of Emperor Kōmei, to marry Shōgun Tokugawa Iemochi.

Andō himself was the target of an assassination attempt in 1862 by six former Mito Domain samurai outside the Sakashita Gate of Edo Castle.

Andō Nobutake (安藤信勇, November 24, 1849-May 24, 1908) was third son of Naitō Masayoshi of Iwamurada Domain in Shinano Province.

He retired in 1872, turning the chieftainship of the clan to Nobutami's younger brother, Nobumori, and later worked as a professor at the Gakushūin Peer's School.