[4] She ran for re-election April 2011 on the PDP platform, but was defeated by Olugbenga Onaolapo Obadara of the Action Congress of Nigeria (ACN), who gained 102,389 votes to Obasanjo Bello's 56,312.

Her political reign finally came to a halt in 2015 when she was ‘crushed’ by Senator Gbenga Obadara who snatched the Ogun Central Senatorial district from her.

[9][10] In April 2003, on the day of the general elections her car was shot at on Ifo Road in Ogun State.

[11][12] In April 2008, Obasanjo came under investigation by Nigeria's Economic and Financial Crimes Commission (EFCC) due to the investigations involving the former minister of health, Prof. Adenike Grange, and the minister of state for health, Gabriel Aduku, for the embezzlement of public funds.

She maintained this money was spent on a conference on capacity building some members of the health committee attended in Ghana.

A week later a high drama ensued when officials of the EFCC tried to arrest her at her home in the Maitama district of Abuja city, after several simultaneous stake outs by law enforcement officials that had her jumping over her fence to evade arrest by Nigerian law enforcement officers.