Iyiola Ajani Omisore (born 15 September 1957) is a Nigerian businessman, engineer, and politician who served as deputy governor of Osun State from 1999 to 2003.

[1] In August 2006, his father was crowned as the first Olu of Olode Town in Ife South Local Government Area of Osun State.

Omisore holds two engineering degrees and a postgraduate certificate from Brunel University Uxbridge, as well as a PhD in Infrastructure Finance from the International School of Management, Paris, France.

Two years later, he was brought back to Nigeria by its Nigerian division, Drake and Scull (Nig) Ltd where he honed his project management skills.

Even though he was still on trial, he was elected to the Senate to represent Osun East constituency in April 2003 running on the platform of the PDP and served till the expiration of his term in 2007.