Jérôme Pernoo learned to play the cello with Germaine Fleury then Xavier Gagnepain.

He plays in recitals with pianist Jérôme Ducros [fr], on some of the most prestigious musical scenes such as the Wigmore Hall in London, the Théâtre du Châtelet, the Théâtre des Champs-Élysées or la Cité de la musique in Paris.

In September 2008, he premiered the cello concerto that Guillaume Connesson dedicated to him, with the Rouen Philharmonic Orchestra under the direction of Jérémie Rhorer.

He is also the creator and artistic director of the festival "Les Vacances de Monsieur Haydn",[1] located at La Roche-Posay, of which the first edition took place in September 2005.

The sentence handed down by the Paris Criminal Court is accompanied by a ban on engaging in any voluntary or professional activity with minors for ten years.