Jūnikane Station (十二兼駅, Jūnikane-eki) is a railway station in the town of Nagiso, Nagano Prefecture, Japan, operated by Central Japan Railway Company (JR Tōkai).

Jūnikane Station is served by the JR Tōkai Chūō Main Line, and is located 292.5 kilometers from the official starting point of the line at Tokyo and 104.4 kilometers from Nagoya.

[1] The station has two opposed ground-level side platforms connected by a footbridge.

It was elevated to a full passenger station on 1 September 1948.

On 1 April 1987, it became part of JR Tōkai.