Ikegwuonou was born in Jackson, Mississippi to medical professionals, Patty and Fidelis Ikegwuonu, and raised in Madison, Wisconsin.

In addition to football and basketball, Ikegwuonu played center field for his school's baseball team.

Wearing jersey #27, Jack Ikegwuonu recorded 23 solo out of 26 tackles with two stops for a total of 6 yards in losses.

He started all 13 games at right cornerback, switching to jersey #6 from #27 and recording 38 solo out of 41 tackles with 3.5 stops for a total of 14 yards in losses, caused a fumble and recovered another for a 50-yard touchdown return.

He started all 13 games at right cornerback, recording 19 solo out 24 tackles with a league-high fifteen pass deflections and one interception for a 2-yard loss.

[6] In November 2014, Ikegwuonu and his twin brother were arrested in Madison, Wisconsin, for allegedly committing five armed robberies.