The film stars the regular Jackass cast of Johnny Knoxville, Bam Margera, Ryan Dunn, Steve-O, "Danger Ehren" McGhehey, Dave England, Preston Lacy, Wee Man, and Chris Pontius.

The film was theatrically released in the United States in the 3D format on October 15, 2010, by Paramount Pictures, marking the tenth anniversary of the Jackass television series.

[4] Leftover film footage scenes was incorporated as a extended length feature released as Jackass 3.5, on DVD and Blu-ray on June 14, 2011.

In a matter typical for the characters, they start arguing and quickly get into a slap-fight, with several of the moves especially animated to come out of the screen in a 3D setting.

The opening sequence features each of the cast members lining up, standing in each color of the rainbow, while an operatic version of the Jackass theme song "Corona" plays.

Once Johnny Knoxville introduces the film, each cast member does small stunts by various objects in slow-motion to the tune of "The Kids Are Back" by Twisted Sister.

The most notable stunts and pranks include: Johnny Knoxville being camouflage-painted as a bull charges at him; Bam Margera falling into a pit filled with snakes while attempting to prank Jeff Tremaine; Ryan Dunn and Steve-O playing instruments while a male sheep rams them; Steve-O drinking Preston Lacy's sweat after riding an elliptical machine; Bam gluing his hands to Preston Lacy and Phil Margera's chest with super glue; Ehren McGhehey getting his crooked tooth pulled by Bam's Lamborghini; Dave England playing tetherball with a beehive against Steve-O; Preston Lacy getting a football kicked into his face by professional NFL kicker Josh Brown; Wee Man participating in a bar brawl with other little people; and Chris Pontius flying an RC helicopter while it is tied to his penis.

The final stunt involves Steve-O being launched high into the air while inside a full port-a-potty connected to bungee cords.

The following closing skit is done in a similar fashion as the introduction, as Knoxville announces he's about to "end the movie", then triggers an old-fashioned dynamite plunger; after the rest of the crew is disappointed by the initial explosion being a mere puff of air out of a nearby piñata, everything in the room is destroyed in a series of large explosions, as the blown-up objects are thrown at the cast (like the opening, all shown in slow-motion) to the tune of Pyotr Ilyich Tchaikovsky's 1812 Overture.

[8] According to Deadline Hollywood, a stunt called "The Heli-cockter" was filmed and shown to Paramount executives in its 3D format to greenlight the project.

"[15] During filming, recurring guest cast member Loomis Fall suffered a compound fracture of his clavicle after an improper landing during a stunt involving an umbrella and a jet engine.

"[19] At the 2010 MTV Movie Awards, Tremaine said filming was nearly finished but they had not shot internationally yet but intended to shoot "a couple of bits".

Deleted scenes that were filmed, but got cut out of both Jackass 3D and Jackass 3.5 include: "BB Gun Nipple Piercing", where Wee Man shoots Steve-O in the nipple with a BB gun; "Bed Sled", where Chris Pontius and Dave England slide down a snowy mountain on an inflatable bed; "Super Mighty Glue Goatee", where Johnny Knoxville puts super mighty glue on his chin and sticks it to Phil Margera's hairy chest; "Banana Gauntlet", where Wee Man, Dave, and Bam Margera slide on a lubed up table with banana peels while they're dressed up as gorillas, and trying to avoid the bananas that are swinging in their way; and "Piss Drink", where Steve-O uses Knoxville's catheter for Knoxville's torn urethra as a straw to drink his piss.

The website's critical consensus reads: "The Jackass gang might be running out of gross-out stunts, but this installment contains plenty of brilliantly brain-dead comedy -- and the 3-D adds a pungent new dimension.

[35] Michael Phillips of the Chicago Tribune criticizes the film describing it as "reductive, insanely violent slapstick" but he accepts that is the idea.

[36] Roger Moore of the Orlando Sentinel complains that the performers "aren't getting better, they're getting older" and the stunts that were cute ten years ago now seem forced and a little desperate.

[42] The most notable added bits include: Johnny Knoxville attempting to skate on full speed treadmills, Bam Margera skating through four walls made of drywall, Steve-O getting his ass bit by an alligator snapping turtle, Ryan Dunn running on a row of chairs while wearing binoculars, Dave England BASE jumping off a motorcycle, Chris Pontius getting his penis pecked by a woodpecker, Wee Man scaring members of the cast while he's camouflage painted in the hallway, Preston Lacy getting hit on his head by a ball attached to bungee cord, and Ehren McGhehey unsuspectingly getting electrocuted by defibrillators while he's sleeping.

In describing the sequel in an interview conducted prior to Jackass 3D's theatrical release, Johnny Knoxville said, "We shot two movies worth of material.

[47] The DVD was released in Australia on August 3 as part of an eight-disc box-set which also includes the other movies, all three volumes of the television series and the Lost Tapes.

In March 2012, Johnny Knoxville discussed the possibility of a fourth film, saying "we're keeping our mind open" and "I've got 50–60 ideas on top of all the stuff we didn't get to shoot.

"[49] During Bam Margera's September 18, 2012 interview on The Howard Stern Show about Jackass he said: "There's going to be a whole movie about Knoxville's grandpa character."

The film was dedicated to cast member Ryan Dunn, who died in 2011 following a fatal car crash.

[51] In August 2010, Rivers Cuomo confirmed that the song "Memories" performed by Weezer will be featured in the film.