"Jackie Down the Line" is the band's first song to chart in the United States, reaching number 40 in the Billboard Adult Alternative Airplay.

Joe Taysom, writing for Far Out Magazine described "Jackie Down the Line" as a track that fits more in the darker sound of the band.

Specifically, Taysom said: "Rather than being a dancefloor filler, the heartfelt track retains that sense of gloom associated with frontman Grian Chatten thanks to his confessional, self-loathing brand of lyricism which has made him emerge as one of the great modern-day songwriters.

The music video was directed by Hugh Mulhern and produced by Alexander Handschuh, Kate Brady, and Laura Clayton.

Fontaines D.C. first performed the song live on 14 January 2022 on The Tonight Show Starring Jimmy Fallon.