He has worked with a variety of artists, including the Cars, U2, R.E.M., the Killers, Robbie Williams, Snow Patrol, Bloc Party, Two Door Cinema Club, AFI, the Hives, Weezer, One Direction, Silversun Pickups, Editors, Modest Mouse, Lonnie Holley, and Taylor Swift.
Jacknife Lee has also remixed a variety of artists' work including a version of Run-DMC's "It's Tricky 2003", the Future Sound of London's "The Mello Hippo Disco Show" and versions of U2's "Vertigo" which was limited released onto 7", 10" and 12" vinyl, Christina Aguilera, TLC, Pink, Blur, Radiohead, Missy Elliott, Busta Rhymes, Eminem, the Raveonettes, Kraftwerk, New Order, and Kasabian.
's Accelerate, Bloc Party's Intimacy, Two Door Cinema Club and Crystal Castles.
[2] Lee supported Bono's "The Stories of Surrender" theater tour in 2022[3] and 2023[4] as musical director, keyboardist and percussionist.
On 24 July 2023, Lee, Lol Tolhurst, and Budgie announced their album Los Angeles, released on 3 November by PIAS Recordings.