[3] The county is named for Andrew Jackson, a hero of the War of 1812 who was subsequently elected President of the United States.

[6] Tribes that inhabited the area in the Colonial period included with Mingo, Lenape, and Shawnee.

Westward expansion by American pioneers displaced the Indigenous People who were killed in wars or relocated to the Great Plains and placed on reservations following the passage of the Indian Removal Act.

The pioneer settlers cleared the land for farming and developed industries around which towns and cities grew.

It met the growing demand for iron in the developing United States of America.

The importance of the furnaces in the Hanging Rock region grew tremendously during the American Civil War.

Iron produced in Jackson County was sold to manufacturers under the trademark, "Anchor".

[6] The era of iron production in Jackson County began to wane in the years following the Civil War.

A combination of a lack of ore and charcoal helped bring about the end of the iron era.

Remnants of the Jefferson Iron Furnaces are found in Jackson Lake State Park.

In 2010 16.5% were of German, 12.9% American, 11.3% Irish, 10.4% English, 5.2% Welsh, 2.4% Scottish, and 1.6% Ulster Scot.

As of the 2010 United States Census, there were 33,225 people, 13,010 households, and 9,028 families living in the county.