Jacobo Fitz-James Stuart y Ventimiglia, 15th Duke of Alba, GE (3 June 1821, Palermo, Sicily – 10 July 1881, Madrid, Spain) was a Spanish nobleman.

He was a brother-in-law of Napoleon III through his wife, sister of Empress Eugenie.

He was the son of Carlos Miguel Fitz-James Stuart, 14th Duke of Alba and Rosalia Ventimiglia dei Principi di Grammonte.

He married at Madrid, on 14 February 1848 María Francisca Portocarrero-Palafox y KirkPatrick, 12ª Duchess of Peñaranda de Duero and daughter of Cipriano de Palafox y Portocarrero.

They had three children: The co-lateral titles of this 15 Duke of Alba were: