[2] After Houphouët-Boigny's death in 1993, Oble was one of the founding members of the Rally of the Republicans with her brother Vincent Lohoues Essoh, who later became Minister of Construction and Town Planning under the transitional government of Robert Guéï.

After the election of Ellen Johnson Sirleaf in neighbouring Liberia in 2005, many women encouraged her to run for the presidency.

[5] After his election, she was appointed as his spokesperson,[5] and then from 5 December 2010 to 11 April 2011, she served as Minister of Education in the Gilbert Aké government, which was not recognised by the international community.

After Gbagbo's arrest on 11 April 2011, bringing an end to the Second Ivorian Civil War, she was the only minister not disturbed by the new leaders.

[5] Oble returned to her work as an academic at Université Félix Houphouët-Boigny in Cocody and ruled out running in the 2015 presidential election.