[3] Jacquemus was born in Salon-de-Provence, France into a family of farmers; his father occasionally sang in metal bands and his mother raised him.

[4] In 2008, at the age of 18, he went to Paris, where he studied for a few months at the École supérieure des arts et techniques de la mode (ESMOD) like Olivier Rousteing.

Having achieved initial interest, his pieces were carried in stores such as Opening Ceremony in New York, Broken Arm in Paris, Gago in Aix-en-Provence and Dover Street Market in London.

[19] On 24 June 2019, Jacquemus organized a parade to celebrate ten years of the brand, hosting its new collection, Le coup de soleil, in a lavender field.

"Having this imagery in mind, we designed women's athletic wear with sensuous details and neutral colors, along with my own interpretation of the Humara, my favorite Nike shoe", said Simon Porte Jacquemus when asked about the inspiration behind the footwear pieces.

[28] Jacquemus stated in October 2024:[29] I value my independence, I want to pass the company on to my children, but I have to break the glass ceiling by finding the right partner who will remain a minority shareholderThe brand has stores in Avenue Montaigne in Paris, SoHo, Manhattan and New Bond Street, London.

[32] Porte married French digital agent Marco Maestri[33] on 28 August 2022 at the town hall of Charleval, Bouches-du-Rhône.