Audiard made his feature film directorial debut with See How They Fall (1994), followed by Read My Lips (2001), The Beat That My Heart Skipped (2005), and Rust and Bone (2012).

[1] He began his screenwriting career in the 1980s with films including Réveillon chez Bob!, Mortelle randonnée, Baxter, Fréquence Meurtre, and Saxo.

In 1994, he directed See How They Fall (French: Regarde les hommes tomber), a road movie starring Mathieu Kassovitz and Jean-Louis Trintignant.

[4][5] Audiard is one of the first filmmakers to participate in LaCinetek's project, a streaming platform where the films are curated exclusively from lists of favorites by acclaimed directors.

He has released some music videos, among them Comme Elle Vient by Noir Désir in which all the actors were deaf-mute and interpreted the lyrics of the song in sign language.

The beginning of the feature (a sequence with subtitles) created a minor scandal; it displayed three women discussing politics who come to the conclusion that "it is better to be deaf than to listen to that".