From 1622 to 1627, he carried out stucco work to accompany the paintings of Domenichino on the high altar of Sant'Andrea della Valle and in San Lorenzo in Miranda.

[2] Appointed Sculpteur et peintre ordinaire du roi in 1631, Sarazin made a number of works for Louis XIII and his wife Anne of Austria, particularly portraits and tomb sculpture, most of which were later destroyed.

[2] Other royal works include the Caryatides of the Pavillon de l'Horloge, in the center of the west wing of the Cour Carrée (Square Court) of the Palais du Louvre.

[2] His main assistants were Guérin, de Buyster, Gérard van Opstal and later Pierre Le Gros the Elder, all of whom in turn became prominent sculptors in the service of Louis XIV.

Already in 1648, Sarazin received the commission for the large funeral monument for the heart of the prince de Condé for the Église Saint-Paul-Saint-Louis in Paris.

He had brought the classical early Baroque style of the Bolognese painters and the restrained playfulness of the sculpture of François Duquesnoy from Italy to France.