Jaime Otero Calderón (19 January 1921 – 15 February 1970) was a Bolivian congressman, mayor, diplomat, cabinet minister, political leader, intellectual, and journalist.

Jaime Otero Calderón and his brothers attended La Salle catholic school where he was very active in the literary arts.

In 1949, Jaime Otero Calderón became legal counsel and administrative manager in the oil fields of Yacimientos Petrolíferos Fiscales Bolivianos (YPFB) in Camiri, Santa Cruz.

The Pachakutismo later dissolved and many of its members, Otero among them, joined the growing Revolutionary Nationalist Movement (MNR) that was led by Víctor Paz Estenssoro.

He reported to the Friends of the city, an independent watchdog organization, that the resources of the municipality were barely enough to "pay salaries and buy brooms to sweep the streets", and did not allow him to initiate needed public works.

On March 13, 1969, after being jailed once again for allegedly participating in subversive activities against the government, Otero wrote a letter to the Minister of the Interior, Cap.

[5] A few weeks before his death he expressed to his wife, Rosario, his grave concern about information that he had received regarding a major state crime that was severely damaging to Bolivia.

In the early hours of Sunday, February 15, 1970, Otero was brutally murdered inside his family's printing business, the Editorial e Imprenta Artística.