[4] During his studies he participated in a number of performances organized by the Fryderyk Chopin University of Music and the Aleksander Zelwerowicz National Academy of Dramatic Art.

[13][14][2] Orliński's debut solo album, Anima Sacra, was released on the Erato label on 26 October 2018, with music by orchestra Il Pomo d'Oro conducted by Maxim Emelyanychev.

[19] A second album Facce d'amore, consisting of "a wide-ranging and well-chosen collection devoted to the many faces of love" from operas by Cavalli, Boretti, Bononcini, Scarlatti, Handel, Predieri, Matteis and Conti, prompted reviewer Brian Robins to commend the singer's "talents as a dramatic singer" and his stylish ornamentation, summing up his voice as "sweet-toned".

[22][23] In 2021, he received a Grammy Award nomination in the Best Opera Recording category for his performance in Handel: Agrippina conducted by Maxim Emelyanychev (Il Pomo d'Oro).

[24] That year he also performed early music by Italian composers with Il Pomo d’Oro ensemble, conducted by Zefira Valova, at the Théâtre du Capitole in the southwestern French city of Toulouse.

In January 2022, he debuted at London's Royal Opera House in the role of Didymus in Katie Mitchell's production of George Frideric Handel's oratorio Theodora.

[27] A complete recording of the original Vienna version of Orfeo ed Euridice conducted by Stefan Plewniak was released in 2024, where one reviewer noted the "touching simplicity [Orliński] brings to the role".

He sang Viens Hymen from Jean-Philippe Rameau's opera Les Indes galantes becoming the first artist from Poland to perform at an Olympic Games opening ceremony.

[38] In 2019, he took part in a photo shoot at the Royal Baths Park in Warsaw and subsequently appeared on the cover of the first edition of Vogue Poland Man magazine.

[41] Orliński joked that someone else was profiting off him when a fan's notebook, purchased from Amazon, read "Sorry I Wasn’t Listening, I Was Thinking About Jakub Jozef Orlinski”.