[2] Voráček scored 9 goals and 29 assists for 38 points in 80 games during his rookie season, helping the Blue Jackets make the Stanley Cup playoffs for the first time in franchise history in 2009.

On 23 June 2011, Voráček was traded (along with first- and third-round picks in the 2011 NHL Entry Draft) to the Philadelphia Flyers in exchange for Jeff Carter.

[6][7] Upon signing, Voráček was expected to fill the gap left by Jágr, who had departed weeks prior via free agency to Dallas, on the Flyers' top line, alongside Claude Giroux and Scott Hartnell.

[8] Voráček returned to the Czech Republic to play for HC Lev Praha of the Kontinental Hockey League (KHL) during the 2012–13 NHL lockout.

The goal, unassisted, was scored just ten seconds into overtime against Jets goaltender Ondřej Pavelec at the MTS Center in Winnipeg.

[13] Playing in all 82 regular season Philadelphia games, Voráček finished the year with 22 goals and 59 assists for a career-high 81 points, tying him for fourth in the NHL lead alongside the Washington Capitals' Alexander Ovechkin.

[24][25][26] On 6 November 2022, while playing in the 2022 NHL Global Series in Tampere, Finland, he sustained a concussion after being hit in the face with a high stick by Dryden Hunt of the Colorado Avalanche, and missed the remainder of the 2022–23 season.

[27] On 2 March 2023, the Blue Jackets traded Voráček and a sixth-round pick in the 2023 NHL Entry Draft to the Arizona Coyotes in exchange for Jon Gillies.

[30] After spending the entire 2023–24 season on the Coyotes' long-term injured reserve list,[31][32] Voráček formally announced his retirement on 23 April 2024.

[33][34] In September 2023, while still on injured reserve with the Arizona Coyotes, Voráček took a position as an assistant coach with the Czech Extraliga (ELH) team Rytíři Kladno.