[7] While on loan with Brno, Zbořil as a restricted free agent with the Bruins, was signed to a two-year, $1.45 million extension on 14 October 2020.

[citation needed] On 23 January, Zbořil recorded his first NHL point, an assist, in a 6–1 win against the Philadelphia Flyers.

For the first time in his NHL career, Zbořil made the Bruins opening night roster to start the 2021–22 season.

[14] After clearing waivers, he reported to Boston's American Hockey League (AHL) affiliate, the Providence Bruins, where he had not played since the 2019–20 season.

[citation needed] On 8 March 2024, unable to find success in the Bruins organization, Zbořil was traded along with a 2027 third-round pick to the Columbus Blue Jackets in exchange for Andrew Peeke.

[18] Remaining unsigned from the Blue Jackets entering the 2024–25 season, Zbořil signed a professional tryout with the New Jersey Devils on September 5, 2024.