Jalan Kuching–Serian is a major highway in the Kuching, Samarahan and Serian Divisions in Sarawak, Malaysia.

The Kilometre Zero for all roads in Sarawak is the Charles Brooke Memorial in Kuching.

Jalan Kuching–Serian begins from the 3rd Mile Interchange and ends at the Serian Roundabout.

The major section of Jalan Kuching–Serian is the dual carriageway, which begins at the 15th Mile Intersection and ends at the Serian Roundabout.

It was carried by Lebuhraya Borneo Utara (LBU) Sdn Bhd as a turnkey contractor and Zecon Kimlun JV Consortium Sdn Bhd, the main contractor.