Jalan Serian–Tebedu, Federal Route 21, is a major highway in Serian Division, Sarawak, Malaysia.

[1] It is a dual lane road that is maintained by PPES Works Sdn.

Among other major destinations branched out from this route are Riih, Tebakang and Mongkos.

Along this road are many scattered houses, privately owned orchards, churches, primary schools and chapels.

GIATMARA institution of Serian district is also located here.