[7][8][9][10][11] During daytime, this species seeks shelter in various locations such as epiphytes, trees, rock crevices, termite nests, or caves.

[12][13] This species is also known to bask on rocks following heavy rains and to rest on roads and trails during the evening, suggesting crepuscular behavior under certain conditions.

[23][24] Recent surveys have failed to confirm the snake's presence on Great Goat Island, an area dominated by dry limestone forest.

[25] Comprehensive island-wide surveys have been conducted,[26] indicating the snake's presence in various parishes such as Trelawny, St. Anne, Westmoreland, and Hanover.

The snake utilizes both active and ambush foraging strategies, which vary depending on the habitat structure, available food resources, and its life stage.

[31] In captivity, the diet often consists of rats for juveniles and adults, while neonates are typically fed chicks or pre-killed, frozen house mice.

[33][34][29] While there is no published data on the species' relative abundance in Jamaica, research suggests that Black-Billed Parrots experience higher rates of nest predation in ecotones compared to forest habitats.

[38][39] The Jamaican boa's natural populations greatly and constantly declined since the late 19th century, mainly because of predation by introduced species (such as mongooses), human persecution, and habitat destruction.

In-situ conservation of the Jamaican boa is seriously hindered by the lack of information on demographic and ecological parameters as well as by a poor understanding of the population structure and species distribution in the wild.